AMP-activated protein kinase (AMPK) regulates metabolism by sensing changes in the AMP:ATP ratio in eukaryotic cells. The binding of AMP to AMPK and activation of its Ser/Thr protein-kinase domain ...

在一项新的研究中，来自日本熊本大学的研究人员推出了一种新型化合物 HPH-15，评估了HPH-15作为糖尿病治疗药物是否有用，结果发现它具有降 低血糖 水平和防止脂肪堆积的双重功效，有望替代 二甲双胍 ...

中国一个科研团队说，他们发现了一种名为石胆酸（LCA）的胆汁如何能够以类似限制热量，或禁食的方式减缓衰老。《南华早报》（South China Morning Post）19日报导，石胆酸是一种在人类和动物体内自然产生的酸性化合 ...

By enhancing the clearance of neutrophil extracellular traps (NETs) through the AMP-activated protein kinase (AMPK)/scavenger ...

During parasitoid wasp infection, activated immune cells of Drosophila melanogaster larvae release adenosine to conserve nutrients for immune response. S-adenosylmethionine (SAM) is a methyl group ...

Liver acid could be ‘elixir’ to extend life, scientists say - Lithocholic acid boosts muscle regeneration and enhances grip ...

A cutting-edge study has identified medical ozone therapy as a promising new treatment for sepsis-induced acute lung injury (ALI). By enhancing the ...

Researchers at Kumamoto University have developed HPH-15, a compound showing promise in treating type 2 diabetes. It reduces ...

The study, published in Diabetologia, demonstrates that HPH-15 outperforms metformin by activating AMP-activated protein kinase (AMPK)—a critical protein regulating energy balance—at lower doses.

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101402, discusses insights into targeting LKB1 in tumorigenesis.

The study, published in Diabetologia, a top journal in the field of diabetes, demonstrates that HPH-15 outperforms metformin by activating AMP-activated protein kinase (AMPK)-;a critical protein ...