The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme, becomes activated by G-protein molecules associated with the adrenergic receptor. Adenylyl cyclase creates ...

This allows the researchers to draw conclusions regarding the corresponding signaling pathways that are affected. The ...

signaling pathway including the Git2 adenylyl cyclase that produces cAMP. Additional studies showed a role for the Cgs2 phosphodiesterase that hydrolyzes cAMP to AMP. In addition, we identified ...

Instead, the "sperm-swim" switch they are targeting is a cellular signalling protein called soluble adenylyl cyclase or sAC ... at a slightly different pathway to halt sperm swimming, by blocking ...