The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme, becomes activated by G-protein molecules associated with the adrenergic receptor. Adenylyl cyclase creates ...

Combining classical yeast genetics with molecular biology, we identified genes required for both repression and derepression of ƒbp1 transcription, including almost all of the genes of the cyclic AMP ...

This allows the researchers to draw conclusions regarding the corresponding signaling pathways that are affected. The ...

Instead, the "sperm-swim" switch they are targeting is a cellular signalling protein called soluble adenylyl cyclase or sAC ... at a slightly different pathway to halt sperm swimming, by blocking ...