The study found that treatment with progranulin (PGRN), a growth factor, reduced apoptosis through Akt phosphorylation and enhanced neuron survival. To validate the therapeutic effects of PGRN ...
followed by phosphorylation of T58 by GSK3, which is inhibited by PI3K–Akt signalling. Aurora A and MYCN levels increased when synchronized IMR-32 cells entered G2 and the proteins colocalized ...
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