The first section of the book, Cellular DNA Replication, begins with an excellent overview of genome duplication by Thomas J. Kelly and Bruce Stillman, followed by chapters on specific steps in ...
the helix structure is unwound special molecules break the weak hydrogen bonds between bases, which are holding the two strands together this process occurs at several locations on a DNA molecule ...
Original DNA template - DNA is a double helix made of two complementary strands. Each strand can be used as a template to create a new DNA molecule. Free DNA nucleotides – needed to form the new ...
By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...
The central dogma of molecular biology describes the flow of genetic information within a biological system. It states that the genetic information encoded in DNA is transcribed into RNA, which is ...
Chair, Molecular Biology Program, SKI; Director, The Functional Genomics Initiative; Paul A. Marks Chair in Molecular Cell Biology Scientists know that cancer can result from mistakes in DNA repair.
We are interested in the mechanism of chromosome replication, a process that is highly conserved across eukaryotes and that involves the duplication of both the chromosomal DNA and its associated ...
The study is published in the journal PLOS Pathogens. With only seven genes, the BK polyomavirus must use the host cell's DNA replication machinery to produce new viruses. Although the virus was ...