You can get Lyme disease twice, as it's possible any time you get a bite from an infected tick. Lyme disease is a tick-borne illness that causes a "bulls-eye" rash, fever, headache, and fatigue.
A bite from an infected tick can often, but not always, create a “bullseye” rash on the recipient. It can be treated with a course of antibiotics, but symptoms can sometimes persist for months ...