Study identifies pro-inflammatory macrophage subtype with distinct genetic features in inflamed joints of RA patients.

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an ...

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an ...

A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...

Researchers demonstrated for the first time, the presence of a dominant macrophage subtype (CD40-expressing CD206+CD163+) in the inflamed RA synovium, which importantly was associated with disease ...

Several subsets of macrophage have been found to closely associate with metastasis-initiating cells in the tumor microenvironment. A team of researchers at the Johns Hopkins Kimmel Cancer Center (MD, ...

【导读】肿瘤微环境（TME）是由复杂的细胞间通讯所调控的动态系统。具体来说，TME中的巨噬细胞在驱动肿瘤进展方面发挥着关键作用。外泌体是肿瘤细胞与TME之间通讯的关键介质。然而，在结直肠癌（CRC）进展过程中，外泌体介导的肿瘤细胞与巨噬细胞之间的通讯 ...

More recent studies have identified immune-competent cells including macrophages, T cells, natural killer and mast cells in human biopsy specimens from non-ruptured chronic tendinopathic Achilles.13 ...

A new study proposes a better understanding of the site of inflammation in RA which will allow for the development of new treatment strategies or predictive biomarkers which could support the ...

Researchers demonstrated for the first time, the presence of a dominant macrophage subtype (CD40-expressing CD206+CD163+) in the inflamed RA synovium, which importantly was associated with disease ...