The next layer could be a CAMK2 inhibitor like the company’s preclinical AD-201 to promote synaptic plasticity and memory formation. At some point in the treatment course, AD-401 could be added ...

Upon neuronal activation, both isoforms move from the dendritic shaft to spines. The abundance of CAMK2 at synapses suggests that it may have an additional, structural role. Indeed, CAMK2β had ...