Ex vivo CAR T recipients need to be treated with harsh chemotherapy regimens ahead of cell therapy transfusions ... After years of tinkering with design decisions and plans, multiple candidates ...

A prime example is chimeric antigen receptor (CAR) T-cell therapy, where T cells are harvested from the blood of a cancer patient and genetically engineered to recognize an antigen expressed on ...

When making therapies based on CAR-T cells, Tomás and his colleagues noted, “The impact of critical process parameters applied during distinct stages of the cell manufacturing process (T cell ...

Imagine a world where your own immune cells are transformed into cancer-fighting superheroes. This is the promise of CAR-T ...

该研究由上海长征医院徐沪济教授团队领衔，联合华东师范大学和浙江大学医学院第二附属医院共同完成。通过运用CRISPR-Cas9基因编辑技术，他们对健康供体的CAR-T细胞进行了精准改造，成功开发出新一代异体通用型CAR-T疗法。

CAR T-cell therapy is a type of immunotherapy. CAR stands for chimeric antigen receptor. You might also hear it called a type of adoptive cell transfer. CAR T-cell therapy is a very complex and ...

Using real-world data, researchers compared 2 chimeric antigen receptor (CAR) T-cell therapies with a bispecific antibody, teclistamab, in multiple myeloma (MM). Treatment options for patients ...

Yescarta – a CD19-directed genetically modified autologous T-cell immunotherapy investigated in the ZUMA-1 trial – is the first chimeric antigen receptor (CAR) T-cell therapy recommended for ...

CAR-T cell therapies administered in an outpatient setting may be safe and feasible without intensive remote monitoring in hematologic malignancies. Receiving CAR-T cell therapies in an outpatient ...

Chimeric antigen receptor (CAR)-expressing T cell treatments have led to efficient and persisting antitumor responses for several cancer types, and thus offer hope for improved ovarian cancer ...

("Eureka"), Estrella’s parent company. Unlike a traditional CAR-T cell, the unique design of an ARTEMIS ® T-Cell, like EB103 ...