Cell fate decisions are regulated by differentiation factors, which activate transcription programmes that specify lineage and differentiation status. Among these factors, the transforming growth ...
When cells express specific genes that characterise a certain type of cell we say that a cell has become differentiated. Once a cell becomes differentiated it only expresses the genes that produce ...
Our longterm goals are to understand the mechanisms regulating the growth, differentiation and self-renewal of skeletal muscle satellite cells for eventual use in cell-based gene therapy approaches.
We combine genetic and metabolomic approaches to investigate cell-type specific growth requirements and elucidate how flux through central metabolic pathways regulates key cellular activities, ...
cell differentiation, and inflammation, in view of these binding capacities to various RAR receptors. Tazarotene down-regulates the abnormal expression of keratinocytes, epidermal growth factor ...