However, the presence of nucleosomes and the folding of chromatin into 30-nanometer fibers pose barriers to the enzymes that unwind and copy DNA. It is therefore important for cells to have means ...

Human survival is dependent upon an extraordinarily intricate dance that takes place inside every cell and every nucleus. DNA ...

Inside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are ...

To study the mechanisms by which transcriptional deregulation causes neoplasia, we are using a chromatin immunoprecipitation ... profiling of tissue culture cells. Using primary tumor samples ...

Each component of a cell has its own function. Animal and plant cells differ and they have similarities. Nucleus, cell membrane, cytoplasm and mitochondria are four cell components that are found ...

This work presents a valuable finding on how the interplay between transcription factors SOX2 and OCT4 establishes the pluripotency network in early mouse embryos. Despite the high quality of the data ...

Python heart muscles ramp up their force to sustain metabolic activity to maintain increased metabolism during feeding.

Different types of brain cells could age at different speeds ... Aging is known to cause changes to the chromatin of animal models, impacting an individual's lifespan. But the field of research ...

Researchers at the University of Chicago found that the TET2 gene affects RNA modifications, influencing how DNA is packaged ...

We now have the complete DNA sequence of many genomes and are able to decipher the mechanisms that regulate gene expression, configure chromatin architecture ... processes are critical for normal ...

Using multiple approaches, the team uncovered that the use of many developmental programs results from chromatin in neural crest cells being more accessible than expected. Chromatin, a combination ...