In the eukaryotic chemosensory signaling circuit, attractant signals sensed by cell-surface receptors are amplified by a positive feedback loop at the leading edge of the cell. The feedback loop, in ...

The first and often genetically damaged step in this pathway is the interaction between two membrane proteins ... Although the connections between cilia, sterols and Hh signalling promise ...

Primary cilia are organelles with important functions in cellular signaling, morphogenesis and homeostasis. Mutations in genes that regulate cilia architecture or function result in disorders called ...

Primary cilia are organelles with important functions in cellular signaling, morphogenesis and homeostasis. Mutations in genes that regulate cilia architecture or function result in disorders called ...