The complement system has more than 50 soluble and membrane-bound proteins. In innate and adaptive immunity, complement is essential for eliminating foreign pathogens and apoptotic cells.
The complement system consists of a cascade of linked proteins that are activated in response to infection or tissue damage.
Alzheimer's disease is characterized by the presence of neurofibrillary tangles and amyloid-β (Aβ) plaques, which co-localize with various inflammation-related proteins and activated microglia.
Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced interim results from a Phase 1/2a clinical study of ARO-CFB, the company’s investigatio ...