*仅供医学专业人士阅读参考能够个体化定制、初步疗效相当好的治疗性癌症疫苗,这几年算是吊足了大家的期待值,但从最初的梦想到大规模应用,疫苗疗法显然还有很长的路要走,比如对疫苗递送肿瘤新抗原效果和安全性的优化就不能停,科研和临床工作者们想出的新技术新思路 ...
*仅供医学专业人士阅读参考最近在各种微生物身上动脑筋,用它们来增敏免疫治疗的研究可真不少啊,比如奇点糕前两天提过的益生菌新抗原疫苗疗法,还有人想到用基因工程改造细菌,让它们表达关键炎症因子IFN-γ来破解免疫治疗耐药[1],但基于细菌的免疫疗法还有得 ...
研究团队通过口服方式将工程化肠道细菌E. coli Nissle 1917导入果蝇肠道,验证了其能在果蝇肠道位置存活并表现出组成型表达的荧光蛋白活性。工程菌的口服对果蝇日常进食功能、存活率并无宏观影响,并于果蝇24小时进食后在肠道内维持稳定的菌群密度。
He said there may be other gut bacteria that do the same. Probiotic treatments that contain a similar strain of E. coli, called Nissle 1917, might also pose a risk potentially, he added - but ...
The platform technology of Synlogic, Inc., uses synthetic biology to genetically engineer commensal bacteria ( Escherichia coli Nissle) to generate synthetic biotic medicines designed to ...
Most urinary tract infections (UTIs) are caused by the E. coli bacteria, which are treated with antibiotics. But some strains may be resistant to common antibiotic types. For the most part ...
And now there’s another E. coli outbreak. As of right now, the U.S. Food & Drug Administration doesn’t have a lot of ...
Researchers recently discovered another quirk of Escherichia coli Nissle; rather than live in normal tissue, it prefers to live in tumors when they're present in the gut and will actively seek ...
Unlike PCR, the regions are amplified in E. coli, not in vitro, and thus are subject to review by the E. coli replication machinery. Both of these advances present new options for DNA engineering.
“E. coli is a bug that we all have in our intestines,” explains Britain's leading expert on E. coli, the microbiologist Professor Hugh Pennington. “The vast majority of the hundreds of different ...
People not washing their hands after going to the toilet, rather than undercooked meat, is behind the spread of a key strain of E. coli. Experts looked at thousands of blood, faecal and food samples.
The Jurupa Community Services District has lifted a drinking water warning after tests cleared the water supply for any remaining presence of E. Coli in Riverside County. On Wednesday, a water ...