Intron recognition always takes place during the splicing event itself, which is catalyzed by the large spliceosomal machinery comprising five RNA molecules and >100 proteins. In contrast ...

This study provides important insights into the regulation of a retained intron in the mRNA coding for OGT, a process known to be regulated by the O-GlcNAc cycling system, and highlights the ...

"Combining the newer base editors with dual splice editing skipped the exon at a much better rate than we were previously able to with any of the available methods. We were able to show that not ...