In addition, exosome delivery systems struggle with preserving bioactivity and maintaining adaptable miRNA cargoes throughout the entire release period, limiting their effectiveness at different ...

exosome天然存在于体液中，且携带重要的信号分子，有望在多种疾病的早期诊断中发挥作用。例如，尿液中的exosomal mRNA和非编码RNA可做为肾脏疾病的生物标志物；脑脊液中的exosomal miRNA有可能作为神经退行性疾病的生物标志物。Exosome在液体活检中的应用意味着这 ...

Conclusion: The significant difference in total exosome and miRNA levels between lung cancer patients and controls, and the similarity between the circulating exosomal miRNA and the tumor-derived ...

Further, through their cargo-carrying capacity, exosomes facilitate the spread of proteins, lipids, mRNA, miRNA, and DNA, which can contribute to their general therapeutic effects. Beyond their ...

Poor early detection associated with ineffective treatments for advanced disease is responsible for the low 5-year survival rates of patients with lung cancer. To date, there is no screening test ...

This study aimed to evaluate the diagnostic potential of urinary exosomal microRNA-200 family members in Kawasaki disease patients. Methods: Urine samples from 15 Kawasaki disease patients and 15 ...

microRNA detection in very dilute samples (e.g., urine, CSF) can be boosted by first isolating exosomes in the sample and then profiling microRNAs contained in these extracellular vesicles. The gold ...

The ultracentrifugation technique was further used to compare and validate the efficiency of miRNA capture by nanowires. The results revealed that EVs containing miRNAs, including exosomes-unique ...

MSC-NTF -derived exosomes are produced in bioreactors and contain cargo that includes at least one of the following neurotrophic factors, and may contain additional proteins or microRNA molecules.