Physiological extracellular matrix (ECM) calcification or mineralization is restricted to bones, teeth and the hypertrophic zone of growth plate cartilage. In contrast, pathological ECM ...
The Mechanobiology Lab explores how adherent cells can sense and respond to the mechanical stiffness of the extracellular matrix. The goal of the Vascular Engineering Lab is to develop novel ...
Atherosclerosis involves multiple processes including endothelial dysfunction, inflammation, vascular proliferation and matrix alteration. Vascular proliferation contributes to the pathobiology of ...
Hepatic fibrosis is a reversible wound healing response characterized by accumulation of extracellular matrix (ECM), or ... deposition of scar molecules, vascular and organ contraction, and ...