The Role of Ferroptosis Inhibitors The authors discuss the use of ferroptosis inhibitors, such as ferrostatin-1, in assessing ...

The following is a summary of “Unbiased Drug Target Prediction Reveals Sensitivity to Ferroptosis Inducers, HDAC and RTK Inhibitors in Melanoma Subtypes,” published in the December 2024 issue of ...

The accumulation of lipids in hepatocytes in nonalcoholic fatty liver disease (NAFLD) leads to an increase in reactive oxygen species and changes in the intracellular microenvironment, while ...

Overall, this fundamental study identified a novel role of NOLC1 in regulating p53 nuclear transcriptional activity and p53-mediated ferroptosis in gastric cancer. The evidence supporting the ...

The SLC13A3 inhibitor alone reversed the ferroptosis resistance and treated cancers in mice. In combination, the two ...

The authors discuss the use of ferroptosis inhibitors, such as ferrostatin-1, in assessing the relevance of ferroptosis in liver injury. Ferrostatin-1 and its analogs have shown inconsistent ...

Our goal is to design a novel inhibitor by linking already designed but unapproved inhibitors ... Project Title: “The OTX Family of Transcription Factors in Ferroptosis and Retinal Dystrophy and ...

I-Mab Announces Preclinical Data of TJ210/MOR210 at 2020 SITC Annual Meeting Unsaturated fatty acids can fight cancer? Cell sub-journal exclusively reveals the underlying mechanism of "ferroptosis" RE ...