Purpose. The effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors were examined. Pharmacogenetics examines the relationship between single-gene polymorphisms and the ...

Precisely how lowered levels of the gene product, an enzyme called hexoseaminidase A, protect against TB isn't known. Balanced polymorphism may explain why cystic fibrosis is so common- the ...

Genetic markers may help predict response to TNF inhibitor therapy in rheumatoid arthritis, potentially leading to more ...

investigated polymorphisms of the 5-HT transporter-linked promoter region (5-HTTLPR) gene. This gene has a short (S) allele and a long (L) allele; men with the LL genotype are likely to have ...

A research team has recently constructed a global polymorphism genetic map of variable number tandem repeats (VNTRs), termed the NyuWa VNTR Polymorphism Map.

PITX2 expression and Neanderthal-introgressed HS3ST3A1—that contribute to variations in tooth size among modern human ...

Balancing selection, in contrast to directional selection, maintains genetic polymorphism in populations. For example, if heterozygotes at a locus have higher fitness than homozygotes (a scenario ...

This study explores the genetics of human reproductive traits, revealing links to aging, health outcomes, and longevity while ...

Host genetics play a significant role in shaping immune responses to different strains in the influenza vaccine, ...

Salivary DNA was collected using a DNA Genotek kit (ON, Canada), and TaqMan assays analyzed COL5A1 rs12722 C/T and rs10628678 AGGG/- (deletion) polymorphisms. Risk Assessment and Main Outcomes We ...