强直性脊柱炎（AS），这个名字听起来像个冷冰冰的医学术语，但它背后却隐藏着一段关于“基因”和“细菌”的复杂纠葛。许多人都听过“HLA-B27”，这个被誉为强直性脊柱炎“头号疑犯”的基因，但你知道吗？单靠这个基因，并不能完全解释强直性脊柱炎的发病。让我 ...

We think this is a highly genetic-driven disease, with the primary gene involved at this time, we know is HLA-B27. HLA-B27 codes for a protein that is on the surface of inflammation, blood cells.

These include sacroiliitis on imaging, especially in the presence of human leucocyte antigen B27 (HLA-B27). Rheumatologists ...

There is a strong link between the HLA-B27 gene and axial spondyloarthritis. In fact, up to 90% of people with ankylosing ...

Features linking this group of diseases include association with HLA-B27, peripheral arthritis that is typically asymmetric and lower limb predominant, and possibly include sacroiliitis ...

A new study from Shelby County reveals higher disease severity, diagnostic delays, and disparities in Black Americans with ...

This Review provides an update on the evidence for the three main hypotheses of HLA-B27 in the pathogenesis of spondyloarthritis. The authors discuss the current understanding of the effect of HLA ...

强直性脊柱炎（AS），这个名字听起来像个冷冰冰的医学术语，但它背后却隐藏着一段关于“基因”和“细菌”的复杂纠葛。 许多人都听过“HLA-B27 ...