Blood stem cells (hematopoietic cells ... has been gained of the growth factors that induce specific forms of cell differentiation, immortalized PSC lines like these may be induced to produce ...
but rapidly become activated to regenerate the hematopoietic system. We are studying several genes involved in different aspects of stem cell activation, including some that transduce initial signals, ...
We discovered that interferon gamma (IFNγ) promotes hematopoietic stem cell (HSC) division and myeloid differentiation in a mouse model of Mycobacterium avium infection (Nature 2010). Furthermore, ...