The Hippo pathway has been delineated during the past four years (for recent reviews, see refs 3–5).Although primarily worked out in Drosophila, homologues of the pathway components exist in ...

Among these signals, the TGF-β and HIPPO pathways are critical, functioning as tumor suppressors and regulating liver ...

The researchers also looked at how PI5P4K activity influenced other components of the hippo pathway and found that reduced ...

BACKGROUND: Many specialized cells in adult organs acquire a state of cell cycle arrest and quiescence through unknown ...

The scientists used AlphaFold 2 to simulate docking between a component of the hippo pathway and a cell membrane lipid. This image was included on the cover of Science Signaling.

The lab reported in the journal Science that a gene pathway called Hippo inhibits cardiac muscle regeneration during development. View the Science Journal article. Our lab is currently working to ...