【导读】特发性肺纤维化（IPF）是肺癌的一种致命并发症，预后不佳。目前靶向合并特发性肺纤维化（IPF-LC）的肺癌患者的治疗效果不佳。近日，上海交通大学与浙江大学研究人员合作共同在期刊《Oncogene》上发表了研究论文，题为“Senescent ...

While the etiology of IPF is unknown, preventing injury/damage to the epithelium barrier and consequent expansion of fibroblast and extracellular matrix is an appropriate step in the right direction.

There is ample evidence to justify investigating ET-1 blockade as a therapeutic approach in IPF. Data From Animal Studies. Transgenic mice with lung-specific overexpression of the human gene for ...

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease in ... express a receptor on their surface that promotes ...

The study examined one of these brakes, called MKP1—which the team found was expressed at lower levels in fibroblasts from ...

The multiple-Grammy Award winner reportedly died due to Idiopathic Pulmonary Fibrosis (IPF). Let’s delve into rare disease that claimed the maestro's life. IPF is a chronic and progressive lung ...

Current IPF cough treatments are often inadequate, highlighting the need for improved therapeutic strategies and a deeper understanding of underlying mechanisms. The study identifies potential ...

"Moreover, the profile of the statistically significant changes in the biomarkers in response to LTI-03 treatment also suggests that LTI-03 may not only act on fibroblasts, but also on epithelial ...