Negative-pressure pulmonary edema (NPPE) occurs when a large, negative intrathoracic pressure is generated against an obstructed upper airway, causing fluid to shift into the lung interstitium.
The mechanism of cough syncope involves the increase of intrathoracic pressure, which is transmitted to the intracranial circulation, decreasing cerebral blood flow. Cough syncope is seen most ...
Intrathoracic obstruction is most severe during ... is increased during inspiration because of the effect of atmospheric pressure to compress the trachea below the site of obstruction.
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