“Such antibodies offer a novel, more selective and thus safer approach for treating ion-channel-related diseases,” he added. Antibodies are also more versatile than small mol-ecules—they can ...

Sodium channel gene (SCN5A) mutations in 44 index patients with Brugada syndrome: different incidences in familial and sporadic disease. Hum Mutat 2003; 21: 651–2 CrossRef ...

Ion channel diseases as a cause of sudden cardiac death in young people Aspects of their diagnosis, treatment, and pathogenesis Dtsch Arztebl Int 2024; 121: ...

Mitochondrial electrophysiology is a field that has significantly evolved since the discovery of ionic currents in ...

Located in the cell membrane, TRPM8 ion channels are known as receptors that recognize cold and respond to menthol, the ...

Dr. Rasband's team is discovering the functional organization of axons in health as well as disease or injury. The generation, propagation, and modulation of electrical signals in the nervous system ...

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin, the University of Kiel, and the Leibniz Institute of ...

Our laboratory uses a combination of structural biology and biophysical techniques to discover how ion channels and membrane-embedded enzymes function at the atomic level. The proteins we study are ...

Researchers uncover how two mechano-sensing ion channels are essential to maintain ... with implications for inflammatory bowel disease and colorectal cancer. Stem cells constantly adapt to ...

The Diver lab explores the biological functions and molecular mechanisms of understudied transmembrane protein families with the goal of revealing critical knowledge about their roles in human ...