Traditionally, antibiotics have come from natural sources, for instance penicillin, or are modified to achieve broad-spectrum activity. Using a so-called ‘lock and key’ mechanism at the ...

We need new classes of antibiotics, new targets and new mechanisms of action. Antibiotic development has ‘pushes’, what about the ‘pulls’? There is an urgent need to address the pull ...

Superbugs, bacteria that are immune to multiple antibiotics, pose a great challenge to modern medicine. Researchers from the ...