and has proved invulnerable to any attempt by bacteria to mutate and overcome its mechanism of action. The promising new drug is currently in the final preclinical stages with preparations ...

Superbugs, bacteria that are immune to multiple antibiotics, pose a great challenge to modern medicine. Researchers from the ...

The mechanism of action for AMC-109 is lysis of bacterial membranes—it attaches to the outer cell membrane of a bacterial cell and causes it to rupture and die rapidly (Fig. 1). “It’s a ...

a necessary process for bacterial survival. Using high-resolution cryo-electron microscopy, the researchers reveal unprecedented detail of gyrase's action on DNA, potentially opening doors for new ...

a necessary process for bacterial survival. Using high-resolution cryo-electron microscopy the researchers reveal unprecedented detail of gyrase’s action on DNA, potentially opening doors for ...

"We also hope that our findings of a new mechanism of action against these bacterial strains may help in the design of future ...

Viruses that infect and kill bacteria, called phages, hold promise as new treatment types for dangerous infections, including ...

In a new study, Weizmann Institute of Science researchers reveal a bacterial immune system that thwarts the phages’ plot by attaching a small protein molecule to their tails. The components of this ...

an essential bacterial enzyme and a major target for antibiotics (1 Trusted Source New mechanism in bacterial DNA enzyme opens pathways for antibiotic development Go to source). This enzyme ...

A study offers evidence that a single bacterial species -- the host of the phage -- can maintain a diverse community of competing phage species. Knowing how more than one kind of virus can survive ...

Superbugs, bacteria that are immune to multiple antibiotics, pose a great challenge to modern medicine. Researchers have now identified a weakness in the bacterial machinery that drives antibiotic ...