The Vierbuchen laboratory seeks to elucidate fundamental mechanisms governing the production of the myriad neuronal cell types required to build functioning neural circuits. To model these dynamic ...

Neuronal stem cells produce a variety of nervous ... been gained of the growth factors that induce specific forms of cell differentiation, immortalized PSC lines like these may be induced to ...

Our laboratory aims at exploiting recent advances in stem cell biology to develop radically new therapies for degenerative disease and cancer. The main focus in the lab is on the biology and ...

The stage of endogenous neurogenesis can be divided into three steps: proliferation, migration and differentiation. (A) Neural stem cells proliferate at the SGZ. The cells then migrate into the ...

Neural stem cells, found in the central nervous system ... with some studies showing decreased proliferation or altered ...

"It is difficult to study the neural tube development process ... Protocol for fabricating elastomeric stencils for patterned stem cell differentiation, STAR Protocols (2024).

The results revealed that Kif23 is essential for the proper proliferation and differentiation ... motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex ...

Stem cell assays are analytical tools used for studying stem cell properties such as proliferation, differentiation, and viability. These assays are crucial in biomedical research, drug discovery, and ...