Medically reviewed by Susan Bard, MD There are a few reasons why it may take time to heal a big pimple. It's normal for some ...

Isotretinoin is indicated for nodular acne or severe acne that is unresponsive to conventional therapies. The usual dose is 0.5 to 1.0 mg/kg/day for 20 weeks, or a cumulative dose of 120 mg/kg.

Your healthcare provider can prescribe treatment if you have a more stubborn case of acne, including cysts or nodules. Let your healthcare provider know if you have any pimples that are inflamed ...

to reduce inflammation before treatment with isotretinoin. Occasionally, intralesional injection or drainage of cysts and nodules will be helpful in resolving inflammation. Acne conglobata (AC ...