When reactive oxygen species accumulate in cells during oxidative stress, Nrf2 moves into the cell nucleus to activate target genes that trigger an anti-oxidant response. Nrf2 also has a host of ...

In a potential advance for melanoma patients, researchers at ChristianaCare’s Gene Editing Institute have used CRISPR gene editing tools to disable a gene mutation often seen in aggressive forms of ...

The work presented will be of interest to cancer biologists and more broadly to those interested in NSCLC translational studies. Non-small cell lung cancer (NSCLC) is the most common subtype of lung ...

During embryonic development, cells start out as pluripotent, or have the potential to become many different cell types ...

New research from The Wistar Institute and the Perelman School of Medicine has identified the RSAD2/Viperin gene as a ...

which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of ... Novel Treatment Based on Gene Editing Safely and Effectively Removes ...

“You just can’t reduce something as complex as human exploration to a single gene,” he says, laughing. “Genetics doesn’t work that way.” Fortunately for me, I had to wander only a ...

Our behaviors and preferences are profoundly influenced by our genetic makeup, by factors in our environment that affect our genes, and by other genes forced into our systems by the innumerable ...

A University of Alberta research team has found a potential new treatment target for ovarian cancer ... investigate the ...

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