by stabilizing p53. Herceptin (trastuzumab) — a humanized monoclonal antibody specific for the extracellular domain of the receptor tyrosine kinase ERBB2 — is used to treat breast cancers that ...

Overall, this fundamental study identified a novel role of NOLC1 in regulating p53 nuclear transcriptional activity and p53-mediated ferroptosis in gastric cancer. The evidence supporting the ...