Phosphorylation is the most ubiquitous ... revealed that PP1 and calcineurin have sleep-regulating functions. These dephosphorylation enzymes consist of a catalytic subunit responsible for ...

Recent research has observed that chemical modifications called phosphorylation of proteins ... the protein kinases that suppress sleep and the dephosphorylation enzymes that control sleep and ...

as well as a new collection of tau-targeted hetero-bifunctional chimeras such as dephosphorylation-targeting chimeras (DEPTACs), proteolysis targeting chimeras (PROTACs) for pTau, phosphorylation ...