Activator proteins bind to regulatory sites on DNA nearby to promoter regions that act as on/off switches. This binding facilitates RNA polymerase activity and transcription of nearby genes.

Critical to this is the outermost layer of the organ, the syncytiotrophoblast (STB), a single, multinucleated cell that forms from ... so she turned to single-nucleus RNA sequencing (snRNA-seq).

However, DNA is complex and specialized; it "subcontracts" the work of reading the instructions to RNA (ribonucleic acid) molecules and building proteins to ribosome molecules. DNA's ...

In the Protein Engineering and Evolution Unit's latest publication in Nucleic Acids Research, the team presents an engineered RNA methyltransferase, which can be used to study the role of RNA ...