Monepantel is under clinical development by Neurizon Therapeutics and currently in Phase II for Motor Neuron Diseases.

Groundbreaking studies in mice have sparked a frenzy among longevity enthusiasts—but human trials are still in their infancy.

The drug blocks the activity of a protein known as mammalian target of rapamycin (mTOR), which promotes proliferation through the activation of proteins such as S6 kinase. Although the mTOR ...

02 研究发现，雷帕霉素-达沙替尼联合伊立替康-替莫唑胺可显著延长MYCN扩增型复发性神经母细胞瘤患者的无进展生存期 (PFS)和总体生存期 (OS)。

Charles Sawyers and colleagues have conducted a small early-stage clinical study to assess target modulation by the small-molecule inhibitor rapamycin. Rapamycin is approved to treat renal cancer ...

Rapamycin shows promise in extending lifespan in animals, with ongoing research on its anti-aging effects in humans. Could it ...

Lithium, a drug commonly used to treat bipolar disorder and depression, has emerged as a potential therapy for autism ...

The drug rapamycin is being studied for its anti-aging and fertility-preserving benefits — and the results seem promising. Here's what to know.

Lithium has traditionally been used to treat bipolar disorder and depression. However, researchers at the Center for Synaptic ...

Am J Health Syst Pharm. 2010;67(24):2095-2106. Temsirolimus is primarily metabolized by the cytochrome P-450 (CYP) 3A4 isoenzyme to five major metabolites, with sirolimus being the principal ...

Some scientists say that rapamycin can reduce inflammation "by inhibiting a signaling pathway in the body called mTOR — which ...

A groundbreaking discovery has highlighted lithium-;a drug long used to treat bipolar disorder and depression-;as a potential therapy for autism spectrum disorder (ASD).