The rRNA structures also provide binding sites for ribosomal proteins, which help stabilize the overall structure of the ribosome. One of the most remarkable features of rRNA is its catalytic activity ...
Alternatively, and likely dominant in bacteria, RNAP (green) can interact with ribosomal protein bS1 (right, cyan). bS1 binds and guides the mRNA (right, white and glowing) from RNAP into the ...
She was using western blotting to study large ribosomal proteins, employing a protocol with two overnight steps. “Finally, I had that blot, and went to image it, but there was nothing there.
identifying protein degradation pathways altered explicitly in disease and employing this information to develop small molecule probes with therapeutic potential, and 3) elucidating the fundamental ...
particularly efficiently when ribosomal protein bS1 was present, which helps the mRNA unfold in preparation for translation inside the ribosome. The cryo-EM structures of Webster and Weixlbaumer ...
They were able to observe the smooth bending motion of inter-subunit bridge proteins and the spring-like transitions of tRNA between ribosome-binding sites, which had not been previously seen in ...