A comprehensive study identifies sequence features that predict tissue-specific alternative splicing. In contrast to transcription and translation, in which the flow of information from DNA to pre ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes ...

However, the mechanisms that drive this transition are poorly understood. In a study published in mBio, a research team identified alternative splicing—the selective inclusion or excision of introns ...

Computational biologists from the National University of Singapore (NUS) have uncovered how RNA splicing—a crucial process ...

Splicing tapes are used within numerous manufacturing production processes. They can be used to join two parts of a product.

This study provides important insights into the regulation of a retained intron in the mRNA coding for OGT, a process known to be regulated by the O-GlcNAc cycling system, and highlights the ...

Johns Hopkins researchers have developed a powerful new AI tool called "Splam" that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with ...

Alternative splicing is crucial for eukaryotic gene expression and influences protein function and regulation, with mis-splicing linked to numerous diseases. In this webinar, Dr. Megan L Noonan will ...

Splicebio S.L. has gained IND clearance from the FDA for its lead program SB-007, a protein splicing gene therapy to address the root genetic cause of Stargardt disease.

Vigeneron GmbH has received IND approval from the FDA for VG-801, a novel mRNA trans-splicing gene therapy to treat Stargardt disease and other retinal dystrophies associated with mutations in the ...