A comprehensive study identifies sequence features that predict tissue-specific alternative splicing. In contrast to transcription and translation, in which the flow of information from DNA to pre ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes ...

Individual genes express multiple mRNAs by pre-mRNA alternative splicing, alternative polyadenylation or use of alternative promoters (first exons). As a result, individual genes express multiple ...

Alternative splicing promotes adaptation to environmental changes ... a fungal microbiologist at the Leibniz Institute for Natural Product Research and Infection Biology.

In the Cheng lab, we strive to understand the fundamental questions of how RNA regulation controls cellular processes in normal biology and in the context of cancer. Working at the interface of RNA ...

Their study is published in Genome Biology. "Precisely identifying splicing sites is key to understanding how cells interpret genetic instructions," says co-lead author Kuan-Hao Chao, a doctoral ...

This diversity is enabled by a process known as “splicing.” When a cell requires a protein, it generates a copy of the relevant instructions in the cell nucleus. During splicing, this ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could ...