This pathway, an indirect connection to the substantia nigra ... with inhibiting dopamine neurons. Now they show unexpectedly ...

SRY expression is found in a specific subset of tyrosine hydroxylase-expressing neurons in the substantia nigra of males. Tyrosine hydroxylase affects synthesis of dopamine, a stimulatory ...

At 12, 18, and 24 months of age, the number of tyrosine hydroxylase (TH)-positive neurons did not differ in the substantia nigra (SN) between wild-type and parkin KO mice using unbiased stereology; ...

DAT: Dopamine transporter expressed in ventral midbrain regions including the substantia nigra and ventral tegmental area ... See Yasuda and Mayford (2006) Neuron. POMC: proopiomelanocortin is ...

By the time patients are diagnosed with Parkinson’s, most have already lost an estimated 60 to 80 percent of the dopamine-producing cells in a part of their midbrain called the substantia nigra ...

By using a drug against an inflammatory molecule called tumor necrosis factor or TNF, the researchers saw a 50 percent drop in dopamine ... brain called the substantia nigra.