Costimulatory molecules, the signals of which act in tandem with those from the T cell receptor (TCR) to activate cellular immunity, can help fuel antitumor activity. The promise of costimulatory ...

Nutrition encompasses a crucial influence on health and diseases, notably within the domain of cancer, where it intersects ...

A research team from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences has revealed that aging specifically impairs the generation of CD8 + tissue resident ...

This exhaustion is influenced by immune checkpoint receptors, which are inhibitory cell surface receptors that can suppress antitumor immunity ... The development of technologies for NK cell ...

leading to the development of vaccines that stimulate neoantigen-specific T-cell responses and antitumor immunity. Initial studies demonstrated the efficacy of neoantigen vaccines in preclinical ...

Amit Sharma as the first author, has identified GLUT3, a glucose transporter, as essential to the suppressive function of ...

This exhaustion is influenced by immune checkpoint receptors, which are inhibitory cell surface receptors that can suppress antitumor immunity ... The development of technologies for NK cell ...

Investigators of the Vall d'Hebron Institute of Oncology's (VHIO) Growth Factors Group, in collaboration with researchers of the Cancer Research Program of Hospital del Mar Research Institute (HMRIB), ...