初步筛选结果表明，属于肿瘤反应性的T细胞基本都是CD8 + T细胞，且TCR库能够与肿瘤组织 ... （降低其占比），却不影响CD4 + T细胞。 而在配对的肿瘤 ...

因此，CD4和CD8共受体有助于集中Th细胞和CTL对适当的MHC分子的注意力。最新的观点是，双阳性T细胞扫描APC，寻找它们的TCR可以结合的MHC分子。

Advances in single-cell immune profiling now allow simultaneous analysis of CD8+ T cell transcriptomes and TCR repertoires, revealing cellular heterogeneity, clonal dynamics, and functional ...

The decrease in CD4 cells during HIV infection seems to be ... and higher LPS levels were associated with greater activation of CD8 + lymphocytes. CD8 + activation also was found to be higher ...