初步筛选结果表明，属于肿瘤反应性的T细胞基本都是CD8 + T细胞，且TCR库能够与肿瘤组织 ... （降低其占比），却不影响CD4 + T细胞。 而在配对的肿瘤 ...

因此，CD4和CD8共受体有助于集中Th细胞和CTL对适当的MHC分子的注意力。最新的观点是，双阳性T细胞扫描APC，寻找它们的TCR可以结合的MHC分子。

The decrease in CD4 cells during HIV infection seems to be ... and higher LPS levels were associated with greater activation of CD8 + lymphocytes. CD8 + activation also was found to be higher ...

Advances in single-cell immune profiling now allow simultaneous analysis of CD8+ T cell transcriptomes and TCR repertoires, revealing cellular heterogeneity, clonal dynamics, and functional ...