Meier and coauthors found that topotecan improved progression-free and overall survival compared with treosulfan in patients with recurrent ovarian cancer following platinum and taxane-based therapy.

Patients who have relapsed or individuals who do not respond to first-line chemotherapy can be treated with topotecan. Phase II and III studies have confirmed the efficacy of topotecan as second ...

A Randomized Trial of Cisplatin With or Without Topotecan in Advanced Carcinoma of the Cervix GOG 204 (pending publication) A Randomized Trial of Paclitaxel Plus Cisplatin Versus Vinorelbine Plus ...