Fluorescence in situ hybridization (FISH) of interphase nuclei from a fetus has been used to diagnose trisomy 21. In each cell, there are two green spots (LSI 13 SpectrumGreen probe, Vysis ...

A century after Down syndrome was first described, scientists discovered that the root cause of this disorder is a condition called trisomy 21. What strides in research have been made since then?

For Trisomy 21, the chance of a positive result being ... your placenta that's circulating in your blood, so it contains cells from both you and your pregnancy. These fragments are free-floating ...

a topic that is poised to elucidate the basis of numerous mitochondrial alterations frequently observed in Trisomy 21 cells. The Brumbaugh Lab is interested in understanding the function of the stem ...

Recognized for discovery of cell-free fetal DNA in maternal blood and creation of noninvasive prenatal testing (NIPT), used by as many as 50% of pregnant women in the US to ...