A century after Down syndrome was first described, scientists discovered that the root cause of this disorder is a condition called trisomy 21. What strides in research have been made since then?

Fluorescence in situ hybridization (FISH) of interphase nuclei from a fetus has been used to diagnose trisomy 21. In each cell, there are two green spots (LSI 13 SpectrumGreen probe, Vysis ...

In this regard, Hannah Arthur, a CBB/SCR T32 graduate trainee in his group is focused on the molecular determinants that regulate mitochondrial energy production pathways, a topic that is poised to ...

For Trisomy 21, the chance of a positive result being ... your placenta that's circulating in your blood, so it contains cells from both you and your pregnancy. These fragments are free-floating ...

Recognized for discovery of cell-free fetal DNA in maternal blood and creation of noninvasive prenatal testing (NIPT), used by as many as 50% of pregnant women in the US to ...