During a Case-Based Roundtable® event, Andrew H. Lipsky, MD, moderated a discussion on the efficacy and safety of newer BTK ...

Sanofi is still plugging away with its oral BTK inhibitor tolebrutinib in multiple sclerosis, but has decided to abandon efforts to develop the drug for neuromuscular disorder myasthenia gravis.

The decision to discontinue BTK inhibitor treatment for CLL is complex, with emerging data suggesting that time-limited therapy may be feasible in certain cases, particularly when combined with other ...

Initiated Phase 1b dose expansion of NX-5948 in chronic lymphocytic leukemia patient population with Fast Track Designation from the FDAInitiated ...

智通财经APP获悉 ，平安证券发表研报称，BTK 抑制剂的问世是血液瘤治疗的重大突破，二代 BTK 抑制剂凭借更优疗效和安全性，市占率逐年提升。我国每年新发淋巴瘤患者10万人，虽然从发病率远低于一些实体瘤如肺癌，然而该领域靶向疗法的出现，使得临床治疗中淋巴瘤已然可视为慢病管理。患者基数及管理周期长叠加下，血液瘤领域相继出现多款突破十亿美元重磅分子如伊布替尼、泽布替尼、阿卡替尼、维奈克拉等，凸显出不 ...

Capivasertib and venetoclax combination shows efficacy in PTEN-wildtype and PTEN-deficient diffuse large B-cell lymphoma (DLBCL) models, inducing caspase and PARP cleavage and inhibiting tumor growth.

Prof. Varcoe: What do you see as the main differences between drug delivery above the knee (ATK) compared to below the knee (BTK)? Prof. Brodmann: In the ATK space, we have learned a lot about ...

Exscientia plc (Nasdaq: EXAI) today announced three abstracts to be presented at the 36th EORTC-NCI-AACR (ENA) Symposium 2024 ...

Sanofi re­leased new Phase 3 da­ta for its BTK in­hibitor tole­bru­ti­nib in non-re­laps­ing sec­ondary pro­gres­sive mul­ti­ple scle­ro­sis (nr­SPMS), show­ing a 31% im­prove ...

Discover what crypto is and how it works. A cryptocurrency is a digital form of money. They are digital assets created to be used to pay for goods and services. Cryptocurrencies can be used as a ...