This study explores the protective effect of PDE5 inhibition on cardiac myocyte hypertrophy and its impact on the transcriptomic profile of phenylephrine (PE)-induced hypertrophy 1 in neonatal rat ...

These include effects on arterial smooth muscle cells that cause intense peripheral vasoconstriction and stimulation of cardiac myocytes and fibroblasts. The latter promotes phenotypic changes in ...

Several observations from preclinical and short-term clinical studies support a role for sildenafil in the treatment of heart failure patients. The following discussion briefly considers each of ...

Moleculin Biotech, Inc., (Nasdaq: MBRX) ("Moleculin" or the "Company"), a late-stage pharmaceutical company with a broad ...

Objectives To study the expressions of endothelin-converting enzyme (ECE2) at early stages of atrial fibrillation in a rapid paced primary cultured atrial myocyte model. Methods Primary rat atrial ...

The researchers were able to show ... Analysis Reveals an Additional Mechanism Behind Statin Therapy's Heart-Related Benefits in People With HIV Dec. 11, 2024 — Investigators who previously ...

DelveInsight’s “Congestive Heart Failure Market Insights, Epidemiology, and Market Forecast – 2034” report delivers an ...

Titin’s regulated integration and mobility after cell fusion support syncytium formation in culture, while limited diffusion in vivo highlights a key challenge for developing effective cell-based ...

If you are an emoji-using communicator, it should come as no surprise that the red heart emoji has been among the top five most-used emojis since the colored icons were invented. In fact ...

A bodybuilder died suddenly at the gym after going into cardiac arrest. José Mateus Correia Silva, 28, was reportedly working out with his friends when he suddenly went into cardiac arrest and ...