Introduction: Hypoxia-inducible factors (HIF) regulate gene transcription ... concentrations to investigate their relationship with chronic kidney disease (CKD) severity. Methods: pHIF-1α and uHIF-1α ...

Hypoxia is intricately linked to various diseases, including chronic kidney disease, lung diseases, and anemia. Our experimental findings suggest that, in the presence of a predisposition toward ...

Dec. 19, 2024 — Researchers have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's disease in a subset of people.

One such pathway, the hypoxic response pathway, is activated by reduced local oxygen concentrations at the tumor site. Hypoxia-driven gene and protein changes enhance epithelial-to-mesenchymal ...

GSK has made the decision to withdraw Jesduvroq (daprodustat) from the US market. Approved in 2023, Jesduvroq, (HIF-PHI), is ...

When living with chronic pain or illness, it’s important not to let your condition dictate every aspect of your life, but it’s also important to be realistic.Saying yes to invitations that you ...

The finding of numerous nRBCs in the term placenta is non-specific and may indicate acute or chronic fetal hypoxia, maternal diabetes, fetal anaemia, or congenital TORCH infections (toxoplasma, other ...

is unclear and indeed acidosis could simply be a marker of the cause and severity of the hypoxia. In the past much attention has been paid to acute acidosis during labour, but in previously normal ...

People who climb too fast or too high risk acute altitude sickness, which can lead to life-threatening hypoxic brain injury ... despite their acclimation, causing chronic altitude sickness.

You may be surprised if your healthcare provider recommends an antidepressant for chronic pain. Is this because she believes you are depressed? Or can antidepressants help with pain even for people ...

June 11, 2024 — Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study has identified two types of these so-called dysbioses in cystic ...