The definition of successful GPOEM varied across studies. The most common definitions were a one-point reduction in gastroparesis cardinal symptom index (GCSI), a one-point reduction in GCSI with a 25 ...
Sepiapterin (PTC-923 (CNSA-001)) is under development for the treatment of moderate to severe diabetic gastroparesis, tetrahydrobiopterin (BH4) deficiency resulting in hyperphenylalaninemia and ...
Metoclopramide (4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide) is a substituted benzamide derivative (Figure 1) with a chemical structure similar to procainamide but without anti ...
GIMOTI nasal spray was approved by the FDA for the relief of symptoms of acute and recurrent diabetic gastroparesis in adults in June 2020. The new patents, U.S. 17/366,839 and U.S. 17/366,818 ...
One of the key challenges in treating gastroparesis is ensuring effective drug absorption, as delayed stomach emptying often compromises the efficacy of orally administered medications. GIMOTI ...