A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...

These LAMs are characterized by heightened expression of genes involved in lipid metabolism, such as FABP3, FABP4, FABP5, lipoprotein lipase (LPL), and lipase A (LIPA). Importantly, depletion of LAMs ...

Apolipoproteins have many roles in lipid metabolism, which are presented in Table II. Table III lists several major enzymes involved in lipoprotein metabolism that have been identified.

Following digestion and absorption of dietary fat, TG and cholesterol are packaged to form chylomicrons in the epithelial cells of the intestines. Chylomicrons circulate through the intestinal ...

Lipids are the essential macronutrients and are a major energy source for human metabolism. Lipids (including fatty acyls, sphingolipids, glycerolipids, glycerophospholipids, prenols, sterols, ...

Cancer cells may be using lipids to hide from the immune system Date: September 17, 2024 Source: Rockefeller University Summary: New study demonstrates that one type of lipid is so critical for ...

The fatty acid-binding protein 5 (FABP5) regulates keratinocyte homeostasis and is up-regulated in psoriatic tissue, and its knockdown in preclinical psoriasis has beneficial effects. Artelo ...

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a disease in which lipids (cholesterol) and other substances accumulate in plaques on the arterial wall, causing the vessels to harden and narrow, and increasing the risk of severe cardiovascular ...