The following is a summary of “Unbiased Drug Target Prediction Reveals Sensitivity to Ferroptosis Inducers, HDAC and RTK Inhibitors in Melanoma Subtypes,” published in the December 2024 issue of ...

The accumulation of lipids in hepatocytes in nonalcoholic fatty liver disease (NAFLD) leads to an increase in reactive oxygen species and changes in the intracellular microenvironment, while ...

The Role of Ferroptosis Inhibitors The authors discuss the use of ferroptosis inhibitors, such as ferrostatin-1, in assessing ...

The effective relief of osteoarthritis symptoms from deterioration has been confirmed by clinical treatment with multiple ferroptosis inhibitors. At the same time, it should be reminded that the ...

Overall, this fundamental study identified a novel role of NOLC1 in regulating p53 nuclear transcriptional activity and p53-mediated ferroptosis in gastric cancer. The evidence supporting the ...

In TAO, the inflammation and fibrosis of ocular tissues are frequently accompanied by the accumulation of intracellular iron and heightened oxidative stress. Inhibitors of ferroptosis may offer a more ...

The Role of Ferroptosis Inhibitors The authors discuss the use of ferroptosis inhibitors, such as ferrostatin-1, in assessing the relevance of ferroptosis in liver injury. Ferrostatin-1 and its ...

The authors discuss the use of ferroptosis inhibitors, such as ferrostatin-1, in assessing the relevance of ferroptosis in liver injury. Ferrostatin-1 and its analogs have shown inconsistent ...